The present invention relates to compounds of the Formula I wherein R<；SUP>；1<；/SUP>；, R<；SUP>；2<；/SUP>；, R<；SUP>；3<；/SUP>；, R<；SUP>；4<；/SUP>；, R<；SUP>；6<；/SUP>；, R<；SUP>；7 <；/SUP>；and A are as defined. Compounds of the Formula I have activity inhibiting production of Abeta-peptide. The invention also relates to pharmaceutical compositions and methods for treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.本發明是有關一種如式I之化合物；I；其中R1、R2、R3、R4、R6、R7、及A係如以下所定義者。式I化合物具有抑制Aβ－肽產生之活性。本發明亦有關用於治療哺乳動物疾病與病症（如神經退化性及/或神經病學之病症（如阿玆海默氏症））的藥學組成物與方法，包含式I之化合物。
