A handle assembly and a stapler comprising same. The handle assembly comprises: a first handle (1) and a second handle (2), the first handle (1) being provided with a sliding slot (41) and a sliding block (42); and a first pointer (81) and a second pointer (82). The sliding block (42) is located at a second section (412) of the sliding slot (41); the first handle (1) is rotated in a second direction until the second handle (2) abuts against the sliding block (42); the second handle (2) is connected in a linkage manner to the first handle (1); the sliding block (42) pushes a second end (822) of the second pointer (82) to rotate in the second direction. The handle assembly is divided into the first handle (1) and the second handle (2); when the stapler does not reach a firing state, the first handle (1) may be pressed, but the second handle (2) does not rotate, and the stapler is not fired; the pointers are divided into the first pointer (81) and the second pointer (82), and when the first handle (1) and the second handle (2) rotate together, the sliding block (42) may push the second pointer (82) to rotate, so that the pointer does not block the rotation of the handle assembly, the smooth movement of the instrument is ensured when the stapler is fired, and the user experience is improved.L'invention concerne un ensemble poignée et une agrafeuse le comprenant. L'ensemble poignée comprend : une première poignée (1) et une seconde poignée (2), la première poignée (1) étant pourvue d'une fente coulissante (41) et d'un bloc coulissant (42); et un premier pointeur (81) et un second pointeur (82). Le bloc coulissant (42) est situé au niveau d'une seconde section (412) de la fente coulissante (41); la première poignée (1) est tournée dans une seconde direction jusqu'à ce que la seconde poignée (2) vienne en butée contre le bloc coulissant (42); la seconde poignée (2) est reliée de manière articulée à la première poignée (1); le bloc coulissant (42) pousse une seconde extrémi