PROBLEM TO BE SOLVED: To provide novel Endo180 enhancers and cosmetics that can enhance Endo180 expression in dermal fibroblasts.SOLUTION: The present invention provides Endo180 enhancers comprising collagen peptides with an average molecular weight of 300 or more and 5000 or less, and cosmetics comprising the Endo180 enhancers.SELECTED DRAWING: None【課題】真皮線維芽細胞におけるEndo180の発現を亢進し得る、新規なEndo180亢進剤及び化粧料を提供する。【解決手段】平均分子量が300以上5000以下であるコラーゲンペプチドを含有するEndo180亢進剤、及びこのEndo180亢進剤を含有する化粧料。【選択図】なし