您的位置: 首页 > 农业专利 > 详情页

TECHNOLOGY FOR IN VIVO SUGAR CHAIN EXTENSION BY TRANSFER OF GLYCOSYLTRANSFERASE GENE
专利权人:
发明人:
申请号:
JP20060545417
公开号:
JP2007514442(A)
申请日:
2004.12.16
申请国别(地区):
日本
年份:
2007
代理人:
摘要:
Using microarray-based profiling of isogenic prostate cancer xenograft models, we found that a modest (2-5 fold) increase in androgen receptor (AR) mRNA was the only expression change consistently associated with developing resistance to anti-androgen therapy. Increased levels of AR confer resistance to anti-androgens by amplifying signal output from low levels of residual ligand and altering the normal response to antagonists. This invention provides cell based assays for use in the examination of new therapeutic modalities and provides insight toward the design of novel anti-androgens.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充