Diagnosing and treating alzheimers disease using annexins with labeled with a radionuclide

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专利权人:

Neurosn; Inc.

发明人:

Stevenson, Nigel R.,Gonzales, Gilbert R.

申请号：

AU2014268593

公开号：

AU2014268593A1

申请日:

2014.05.21

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

Alzheimers disease is treated by attacking hyperactive microglia preferably before excessive beta amyloid is built up by administering tin-117m-DOTA annexin V. This compound in low radioactive doses selectively binds to the aged hyperactive microglia and emits a conversion electron which effectively induces apoptosis in the hyperactive microglia. A follow-up treatment of tin-annexin Al can be administered to repair the blood brain barrier. The annexin Al assists in the repair of the blood-brain barrier and the associated tin-117m will induce apoptosis in aged hyperactive microglia associated with the blood brain barrier.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/