A medical sampling device, a method of manufacturing the device, and methods of testing and diagnosis using the device； a sampling dressing comprising the device, a method of manufacturing the dressing, and a method of diagnosis using the dressing； and a therapy dressing comprising the device, a method of manufacturing the dressing, and a method of treatment using the dressing. The a sampling device comprises a biodegradable porous scaffold which in use lies in contact with tissue to be sampled and comprises a fluid, in particular a reversibly thermoswitchable gel.
