THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC;YALE UNIVERSITY
发明人:
Martha Somerman,Brian Foster,Emily Chu,Demetrios Braddock,Enrique De La Cruz
申请号:
US16765420
公开号:
US20200323895A1
申请日:
2018.11.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A method of treating or preventing periodontal disease in a subject comprises administering to the subject an inhibitor of ecto-nucleotide pyrophosphate/phosphodiesterase-I (ENPP1). An ecto-nucleotide pyrophosphate/phosphodiesterase-I (ENPP1) inhibitor and pharmaceutical compositions for use in treatment or prevention of periodontal disease or for increasing cementum formation are also disclosed.