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TARGETING cGMP-RELATED PHOSPHODIESTERASES TO REDUCE CYST FORMATION IN CYSTIC KIDNEY DISEASE, AND RELATED MATERIALS AND METHODS
专利权人:
Rita Maria Cunha de Almeida;Indiana University Research and Technology Corporation
发明人:
Robert Bacallao,James A. Glazier,Sherry G. Clendenon,Rita Maria Cunha De Almeida
申请号:
US15557796
公开号:
US20180078559A1
申请日:
2016.03.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein is the identification of cGMP-specific phosphodiesterase upregulation in cystic kidney diseases. Also described is the use of cGMP-specific phosphodiesterase inhibitors for preventing the progression and/or treatment of cystic kidney diseases. Other aspects described provide medicaments for preventing the progression and/or treating cystic kidney diseases, and methods of diagnosing cystic kidney disease.
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