ROBERT BRUNO,FAUVEL BÉNÉDICTE,CHEVE GWÉNAËL,YASRI AZIZ,LARBOURET CHRISTEL,LECONET WILHEM,CHARDES THIERRY,LARROQUE CHRISTIAN,PELEGRIN ANDRÉ
申请号：
IN2417/MUMNP/2013
公开号：
IN2013MN02417A
申请日:
2013.12.23
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
The present invention relates to anti Axl antibodies and uses thereof in diagnostic and therapeutic methods. More particularly the present invention relates to a monoclonal antibody having specificity for Axl comprising an heavy chain variable region comprising SEQ ID NO:2 in the H CDR1 region SEQ ID NO:3 in the H CDR2 region and SEQ ID NO:4 in the H CDR3 region and a light chain variable region comprising SEQ ID NO: 6 in the L CDR1 region SEQ ID NO:7 in the L CDR2 region and SEQ ID NO:8 in the L CDR3 region. Said monoclonal antibody binds to the extracellular domain of Axl via SEQ ID NO:9 and SEQ ID NO: 10.
