VARIANTS DE VDAC N-TERMINAL ET LEURS UTILISATIONS

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专利权人:

BEN-GURION UNIVERSITY OF THE NEGEV

发明人:

申请号：

EP07736195.4

公开号：

EP2004680B1

申请日:

2007.04.10

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present invention relates generally to variants and peptides of the mitochondrial protein, voltage-dependent anion channel (VDAC) and to polynucleotides encoding same. In particular, the present invention is directed to N-terminal truncated and mutated VDAC and specific amino acid and polynucleotide sequences thereof useful in inhibiting apoptosis, and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with excess apoptosis.

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