Accelerators for modifying unnatural amino acids and unnatural amino acid polypeptides

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专利权人:

アンブルックス，インコーポレイテッド;アンブルックス,インコーポレイテッド

发明人:

ティアン，フェン,ミャオ，ツェンウェイ,ティアン,フェン,ミャオ,ツェンウェイ

申请号：

JP2008540156

公开号：

JP5508716B2

申请日:

2006.11.08

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

Disclosed herein are accelerants for the formation of oxime-containing compounds from the reaction of a carbonyl-containing compound and a hydroxylamine-containing compound. The oxime-containing compound, the carbonyl-containing compound and the hydroxylamine-containing compound can each be a non-natural amino acid or a non-natural amino acid polypeptide. Also disclosed is the use of such accelerants to form oxime-containing compounds, the resulting oxime-containing compounds, and reaction mixtures containing such accelerants.

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