Beth Israel Deaconess Medical Center, Inc.;Trustees of Boston University
发明人:
Ara Nazarian,Edward Rodriguez,Mark Grinstaff
申请号：
US16339659
公开号：
US20190282665A1
申请日:
2017.10.09
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides methods for treating a stiffened joint in a subject that comprise administering relaxin, e.g., a PEGylated relaxin-2, to the subject. The relaxin may be administered intra-articularly as a sustained release formulation. The present invention also provides sustained release formulations in the form of a hydrogel for administering polypeptides that are covalently attached to a polymer, e.g., PEG.
