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DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS
专利权人:
发明人:
ABOUABDELLAH AHMED,HOORNAERT CHRISTIAN,JEUNESSE JEAN,ALMARIO GARCIA ANTONIO
申请号:
IN2332/KOLNP/2006
公开号:
IN252044B
申请日:
2006.08.17
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
Derivatives of piperidinyl alkyl carbamates, preparation method thereof on use of same as FAAH enzyme inhibitors The invention relates to a compound having general formula (I), wherein: m - 1 to 4 n represents =1, 2 or 3 o = 1 or 2 A is selected from among one or more X, Y and/or Z groups X optionally-substituted methylene Y = C2-alkenylene, optionally substituted Z = C3-7-cycloalkyl B = covalent bond or C1-6-alkylene G = covalent bond, O, S, -CH(OH)-, CO, SO or SO2 R1 represents an aryl- or heteroaryl-type group R2 = hydrogen or C1-6-alkyl R3 = hydrogen, C1-6-alkyl, C3-7-cycloalkyl, C3-7-cycloalkyl-C1-3-alkylene. The inventive compound takes the form of a base, an acid addition salt, a hydrate or a solvate. Said compound is suitable for use as FAAH enzyme inhibitors.
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