The present invention relates to a metered droplet medicament delivery device for delivering metered doses of medicament, comprising a proximal and a distal part having opposite distal and proximal ends; a medicament container arranged with a movable stopper; a dose delivery mechanism comprising a plunger rod, operably arranged to act on said stopper; wherein said proximal part and said distal part are releasably connectable to each other, whereby said proximal part comprises a medicament container holder accommodating said medicament container and distal part comprises said dose delivery mechanism with said plunger rod, wherein a plunger rod positioning member engageable with a proximal end of said plunger rod as well as engageable with a proximal area of said distal part for positioning said plunger rod in a longitudinal direction of the device in relation to said proximal area (218, 222).