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COMPOSE HETEROCYCLIQUE, ET INHIBITEUR DE DEGRADATION DE P27KIP1
专利权人:
ASKA PHARMACEUTICAL CO.; LTD.
发明人:
UCHIDA, HIROSHI,ASAGARASU, AKIRA,MATSUI, TERUAKI
申请号:
CA2804225
公开号:
CA2804225C
申请日:
2011.07.01
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
A novel heterocyclic compound or a salt thereofuseful for selectively inhibiting the degradation of p27Kip1is provided. The compound or the salt thereof is representedby the following formula (1) :(formula 1)wherein A represents an alkyl group, a cycloalkylgroup, an aryl group or a heterocyclic group, the groupA may have a substituent; the ring B represents a 5- to8-membered monocyclic heterocyclic ring or a condensed ringcontaining the monocyclic heterocyclic ring, the ring Bmay have a substituent; the ring C represents an aromaticring, the ring C may have a substituent; L represents alinker comprising a main chain having 3 to 5 atoms selectedfrom the group consisting of a carbon atom, a nitrogen atom,an oxygen atom and a sulfur atom, wherein at least one atomin the main chain is a hetero atom selected from the groupconsisting of a nitrogen atom, an oxygen atom and a sulfuratom, the linker L may have a substituent; and n is 0 or1.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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