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HETEROZYKLISCHE VERBINDUNG UND P27-KIP-1-ABBAUHEMMER
专利权人:
LTD.;ASKA PHARMACEUTICAL CO.
发明人:
UCHIDA, HIROSHI,ASAGARASU, AKIRA,MATSUI, TERUAKI
申请号:
EP11800989
公开号:
EP2594555A4
申请日:
2011.07.01
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
A novel heterocyclic compound or a salt thereof useful for selectively inhibiting the degradation of p27 kip1 is provided. The compound or the salt thereof is represented by the following formula (1): wherein A represents an alkyl group, a cycloalkyl group, an aryl group or a heterocyclic group, the group A may have a substituent; the ring B represents a 5- to 8-membered monocyclic heterocyclic ring or a condensed ring containing the monocyclic heterocyclic ring, the ring B may have a substituent; the ring C represents an aromatic ring, the ring C may have a substituent; L represents a linker comprising a main chain having 3 to 5 atoms selected from the group consisting of a carbon atom, a nitrogen atom, an oxygen atom and a sulfur atom, wherein at least one atom in the main chain is a hetero atom selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom, the linker L may have a substituent; and n is 0 or 1.
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中国工程科技知识中心
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