ЛИНДСЛИ Крейг У. (US),КОНН П. Джеффри (US),УИВЕР Чарльз Дэвид (US),НИСВЕНДЕР Коллин М. (US),УИЛЬЯМС Ричард (IE),ДЖОНС Кэрри К. (US),ШЕФФЛЕР Дуглас Дж. (US)
申请号：
RU2011124709/04
公开号：
RU2011124709A
申请日:
2009.12.29
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A compound having a structure represented by the formula: where R is a possibly substituted organic residue containing from 1 to 12 carbon atoms, where each R and R include two substituents independently selected from hydrogen, halogen, OR, nitrile, nitro, SR, N ( R) and a possibly substituted organic residue containing from 1 to 6 carbon atoms； where each R independently represents hydrogen or a possibly substituted C 1-6 aliphatic group, or two R groups at the same nitrogen atom form together with said nitrogen 4 -8 membered g a thermocyclic ring containing 1-2 heteroatoms independently selected from nitrogen, oxygen or sulfur； where R and R are two substituents oriented relative to each other in the syn position, while R and R are independently selected from hydrogen and optionally substituted organic residue containing from 1 up to 6 carbon atoms； where R is selected from hydrogen, halogen, OR, cyano, nitro, SR, N (R) and a possibly substituted organic residue containing from 1 to 12 carbon atoms； where R includes two substituents independently selected from hydrogen, halogen. OR, piano, nitro, SR, N (R) and a possibly substituted organic residue containing from 1 to 6 carbon atoms； where R includes five substituents independently selected from hydrogen, halogen, OR, cyano, nitro SR, N (R) and a possibly substituted organic residue containing from 1 to 6 carbon atoms； or a pharmaceutically acceptable derivative of the compound. 2. The compound according to claim 1, characterized in that R represents an optionally substituted group selected from C3-C12 monocyclic or bicyclic cycloalkyl, C3-C12 monocyclic or bicyclic1. Соединение, имеющее структуру, представленную формулой:где Rпредставляет собой возможно замещенный органический остаток, содержащий от 1 до 12 атомов углерода；где каждый Rи Rвключает два заместителя, независимо выбранных из водорода, галогена, OR, нитрила, нитро, SR, N(R)и возможно замещенного органического остатка, содержащего от 1 до 6 атомов у
