KAUFMANN, GUNNAR JORG FLORIS,FU, YANWEN,PATTERSON, JAMES T.,ZHANG, YAN-LIANG
申请号：
CA3002774
公开号：
CA3002774A1
申请日:
2016.10.24
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention provides programmable universal cell receptors (PUCRs)comprising a catalytic antibody region,a transmembrane domain and a cytoplasmic domain. The PUCRs disclosed hereinmay be conjugated to a specificity agent inorder to program the receptor for specificity to any molecule of interest.Also provided are nucleic acids encoding such PUCRs, andcells expressing the PUCRs. Such cells may be used in treating a variety ofmedical conditions and diseases including cancer and infectiousdiseases.
