JAKOB-ROETNE, ROLAND,LUCAS, MATTHEW C.,THOMAS, ANDREW
申请号:
CA2760746
公开号:
CA2760746C
申请日:
2010.04.28
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention is concerned with isoxazole-pyrazole derivatives offormula I, having affinity and selectivityfor GABA A .alpha.5 receptor, their manufacture, pharmaceutical compositionscontaining them and their use as medicaments. Theactive compounds of the present invention are useful as cognitive enhancer orfor the therapeutic and/or prophylactic treatment ofcognitive disorders like Alzheimer's disease.