JAKOB-ROETNE, ROLAND,LUCAS, MATTHEW C.,THOMAS, ANDREW
申请号:
CA2759598
公开号:
CA2759598C
申请日:
2010.04.28
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention is concerned with isoxazole-thiazole derivatives offormula I, having affinity and selectivityfor GABA A .alpha.5 receptor, their manufacture, pharmaceutical compositionscontaining them and their use as therapeutically activesubstances. The active compounds of the present invention are useful ascognitive enhancer or for the therapeutic and/or prophylactictreatment of cognitive disorders like Alzheimer's disease.