Methods for peptide hydrolysis, compositions for use as peptidases, bacteriostatic and fungicides, kits and uses of active forms of LytM from Staphylococcus aureus or derivatives thereof
The invention relates to new method of peptide hydrolysis, in particular of the cell walls of Gram-positive bacteria, wherein the active form of LytM or derivative thereof is contacted with a peptide substrate, preferably with the cell walls of Gram-positive bacteria, in an aqueous environment of conductivity lower than 10 mS/cm. The invention also relates to composition comprising active form of LytM or derivative thereof and new uses of active form of LytM or derivative thereof.本発明は、とりわけグラム陽性細菌の細胞壁の、ペプチド加水分解の新しい方法に関し、ここで、ＬｙｔＭの活性型またはその誘導体は、１０ｍＳ／ｃｍ未満の伝導性の水性環境において、ペプチド基質、好ましくはグラム陽性細菌の細胞壁と接触する。本発明はまた、ＬｙｔＭの活性型または誘導体を含む組成物、およびＬｙｔＭの活性型または誘導体の新しい使用に関する。【選択図】なし
