Jacob Hendrik Beijnen,Johannes Henricus Matthias Schellens,Johannes Jan Moes,Bastiaan Nuijen
申请号：
US12197432
公开号：
US09089544B2
申请日:
2008.08.25
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Pharmaceutical compositions and methods for the treatment of neoplastic disease and comprising the combination of a taxane, such as docetaxel, with a CYP3A4 inhibitor, such as ritonavir. Methods of treatment of neoplastic disease incorporating the administration of a taxane and the administration of a CYP3A4 inhibitor, either simultaneously or separately, are also included. Further, kits for carrying out the methods are included. Solid pharmaceutical taxane compositions for oral administration comprising a substantially amorphous taxane, a carrier and a surfactant are also included.
