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PYRIDINE AMIDOPYRIMIDINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF
专利权人:
Shanghai Allist Pharmaceuticals; Inc.
发明人:
LUO, Huibing,ZHOU, Huayong,WANG, Shuhui,WU, Yong
申请号:
EP15828199
公开号:
EP3181560A4
申请日:
2015.07.29
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to pyridinylaminopyrimidine derivatives represented by the following formula (I), and pharmaceutically acceptable salts, preparation process and use thereof, wherein R 1 , R 2 , R 3 , R 4 , R 5 , m and A are defined as in the description. Pyridinylaminopyrimidine derivatives of the present invention can selectively inhibit the activity of mutant-type epidermal growth factor receptor (EGFR), have a good inhibition for the cancer cell proliferation, and therefore can be used as a therapeutic agent for treating tumors and relevant diseases.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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