Dicyclic compound as 4 β of α, 2 cigarette alkali type acetylcholine receptors ligand农业专利-农业专业知识服务系统

发明人:: NIROGI, Ramakrishna,罗摩克里希纳．尼罗吉,羅摩克里希納．尼羅吉,MOHAMMED, Abdul, Rasheed,阿卜杜勒．拉希德．穆罕默德,VEERAMALLA, Srinivas,斯里尼瓦斯．维拉马拉,斯里尼瓦斯．維拉馬拉,RAVELLA, Srinivasa, Rao,斯里尼瓦萨．拉奥．拉韦拉,斯里尼瓦薩．拉奧．拉韋拉,AHMAD, Ishti,罗摩克里希纳.尼罗吉,羅摩克里希納.尼羅吉,阿卜杜勒.拉希德.穆罕默德,斯里尼瓦斯.维拉马拉,斯里尼瓦斯.維拉馬拉,斯里尼瓦萨.拉奥.拉韦拉,斯里尼瓦薩.拉奧.拉韋拉

摘要：: The present invention relates to the new dicyclic compound and its derivative of formula (I), prodrug, tautomer, stereoisomer, polymorph, solvate, hydrate, metabolin, N- oxide, officinal salt and include their compositions. The invention further relates to prepare above-mentioned noval chemical compound and its derivative, prodrug, tautomer, stereoisomer, polymorph, solvate, hydrate, metabolin, N- oxide, officinal salt and comprising the method for their compositions. These compounds can be treated and prevented with what is related to the various diseases of 4 β of α, 2 cigarette alkali receptor.本發明涉及式(I)的新的雙環化合物及其衍生物、前藥、互變異構體、立體異構體、多晶型物、溶劑化物、水合物、代謝物、N-氧化物、可藥用鹽以及包含它們的組合物。本發明還涉及製備上述新化合物及其衍生物、前藥、互變異構體、立體異構體、多晶型物、溶劑化物、水合物、代謝物、N-氧化物、可藥用鹽以及包含它們的組合物的方法。這些化合物可用於治療和預防涉及α4β2煙鹼型受體的多種病症。