As 5-HT6 receptors ligand Sulfone compounds农业专利-农业学术服务平台

发明人:: NIROGI, Ramakrishna,罗摩克里希纳．尼罗吉,羅摩克里希納．尼羅吉,SHINDE, Anil, Karbhari,阿尼尔．卡巴里．欣德,阿尼爾．卡巴里．欣德,KAMBHAMPATI, Rama, Sastri,拉马．萨斯特里．坎布汉帕蒂,拉馬．薩斯特里．坎布漢帕蒂,BADANGE, Rajesh, Kumar,拉杰什．库马尔．拜丹吉,拉杰什．庫馬爾．拜丹吉,REBALLI, Ven,罗摩克里希纳.尼罗吉,羅摩克里希納.尼羅吉,阿尼尔.卡巴里.欣德,阿尼爾.卡巴里.欣德,拉马.萨斯特里.坎布汉帕蒂,拉馬.薩斯特里.坎布漢帕蒂,拉杰什.库马尔.拜丹吉,拉杰什.庫馬爾.拜丹吉

摘要：: The present invention relates to the Xin Sulfone compounds of the formula (I) as 5-HT6 receptors ligands and its derivative, prodrug, tautomer, stereoisomer, polymorph, solvate, hydrate, metabolin, N- oxides, officinal salt and include their compositions. The invention further relates to prepare above-mentioned noval chemical compound and its derivative, prodrug, tautomer, stereoisomer, polymorph, solvate, hydrate, metabolin, N- oxides, officinal salt and comprising the method for their compositions. These compounds can treat/prevent the relevant various diseases of 5-HT6 function of receptors with what.本發明涉及作爲5-HT6受體配體的式(I)的新的碸化合物及其衍生物、前藥、互變異構體、立體異構體、多晶型物、溶劑化物、水合物、代謝物、N-氧化物、可藥用鹽以及包含它們的組合物。本發明還涉及製備上述新化合物及其衍生物、前藥、互變異構體、立體異構體、多晶型物、溶劑化物、水合物、代謝物、N-氧化物、可藥用鹽以及包含它們的組合物的方法。這些化合物可用於治療/預防5-HT6受體功能相關的多種病症。