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Heterocycle and carbocyclic derivative
专利权人:
塩野義製薬株式会社
发明人:
甲斐 浩幸,田中 悟,平松 義春,野津 梓,中村 健一郎
申请号:
JP2013557587
公开号:
JP6124351B2
申请日:
2013.02.08
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect, e.g. a compound of Formula (I): wherein R2 is a hydrogen atom or the like; ring A is five- to seven-cycloalkane or the like; C is a carbon atom; Q1 and Q2 are carbon atoms or the like; R9a and R9b are carbon atoms or the like; R6 is cycloalkyl or the like; R7 is a group represented by the formula: wherein ring D is benzene or the like; carbon atom a and b are carbon atoms; ring B is an aromatic carbocyclic ring or the like; s and s′ are 0 or the like; R9 and R9′ are halogen or the like, or the like, or its pharmaceutically acceptable salt.
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