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Heterocyclic ring and carbocyclic derivative
专利权人:
Shionogi & Co.; Ltd.
发明人:
Hiroyuki Kai,Satoru Tanaka,Yoshiharu Hiramatsu,Azusa Nozu,Ken'ichioh Nakamura,Kenichioh Nakamura
申请号:
US14377331
公开号:
US09550763B2
申请日:
2013.02.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect, e.g. a compound of Formula (I):whereinR2 is a hydrogen atom or the like;ring A is five- to seven-cycloalkane or the like;C is a carbon atom;Q1 and Q2 are carbon atoms or the like;R9a and R9b are carbon atoms or the like;R6 is cycloalkyl or the like;R7 is a group represented by the formula:whereinring D is benzene or the like;carbon atom a and b are carbon atoms;ring B is an aromatic carbocyclic ring or the like;s and s′ are 0 or the like;R9 and R9′ are halogen or the like,or the like,or its pharmaceutically acceptable salt.
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