您的位置: 首页 > 农业专利 > 详情页

Synthesis of cantharidin
专利权人:
Inc.;Verrica Pharmaceuticals
发明人:
DAVIDSON, Matthew Gene,EKLOV, Brian Matthew,WUTS, Peter,LOERTSCHER, Brad Melvin,SCHOW, Steven R.
申请号:
AU2018346414
公开号:
AU2018346414A1
申请日:
2018.10.04
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The invention provides synthetic methods for the preparation of cantharidin and analogs thereof. In one aspect, the invention provides an improved Diels-Alder cycloaddition to generate a key intermediate en route to cantharidin and analogs thereof. In yet another aspect, the invention describes a new palladium-mediated carbonylation providing another key intermediate en route to cantharidin and analogs thereof. In addition to synthetic methods, present invention also provides compounds (i.e., intermediates) useful in the synthesis of cantharidin and analogs thereof. Compounds provided herein may have biological activity, and therefore may be used in the treatment of diseases or conditions (e.g., infectious diseases and skin conditions).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充