Motonari Uesugi,Salih J. Wakil,Lutfi Abu-Elheiga,Mizuki Watanabe
申请号:
US14052074
公开号:
US09187485B2
申请日:
2013.10.11
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to methods of treating a disease related to cell hyper-proliferation via administration of a therapeutically effective amount of a compound having a general tripartite structure A-B-C. In the tripartite structure A, B, and C are identical or non-identical structures, for example, but not limited to, heterocyclic, phenyl or benzyl ring structures with or without substitutions and are described in detail herein. The methods may utilize particular compounds, for example, having a piperidinyl, a pyrrolinyl or pyridinyl A ring, a thiazole B ring, and a phenyl C ring which may be further substituted independently.