A system, method and compositions for treating age-related illnesses and conditions is provided. In one embodiment a kit comprises two or more containers, wherein each container comprises a young donor plasma product and indicia comprising information related to the age of donors of the young donor plasma product and wherein the young donor plasma product is sourced from a plurality of donors. The plurality of donors are within an age range at the time of donation all male. The age range includes an upper limit of 25 years of age or less and the lower limit of 16 years of age or more. The young donor plasma product has been processed to remove fractions having an average molecular weight below a predetermined threshold.
