In accordance with some embodiments, systems, methods and media for generating a bone age assessment. In some embodiments, a method comprises: receiving an x-ray image of a subject's left hand and wrist； converting the image to a predetermined size； identifying, without user intervention, a first portion of the image corresponding to the hand and wrist； processing the first portion of the image to increase contrast between bones and non-bones to generate a processed image； causing a trained convolution neural network to determine a bone age based on the processed image； receiving an indication of the bone age； causing the bone age to be presented to a user as the result of a bone age assessment； and causing the bone age and the image to be stored in an electronic medical record associated with the subject.
