STRAND, ROSS,PRENDERGAST, MAURICE JOSEPH,WANG, XIAOLI
申请号：
CA2703078
公开号：
CA2703078C
申请日:
2008.11.04
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to an aqueous oral composition comprising: a)from 0.2% to 3% divalent metal ionscomprising: i. from 0.1% to 1.5% of zinc ions； ii. from 0.1% to 2% of tin (II)ions； and b) a source of fluoride ions； c) a silica dentalabrasive； d) one or more chelants having a MW of less than 1000 and capable offorming water-soluble complexes with the zinc ions,wherein the chelants comprise less than 0.2% linear polyphosphates having achain length of four or more； e) an orally acceptablecarrier comprising at least 20% total water； wherein the pH of the compositionis from 5 to 6.5, the molar ratio of the chelants to thedivalent metal ions is at least 0.70: 1 and at least 80% by weight of thetotal zinc ions are solubilised within the composition. Thecomposition of the invention has been found to give improved antimicrobialactivity from the zinc / stannous combination withoutsignificant taste, staining or stability problems, compared to compositionshaving lower levels of chelants.
