A protective sheath device for use in protecting lead wire cables from contamination during use in a hospital or other medical setting is described. A glove-like component having fingers, with each finger intended to protect one lead wire, is placed on a base or mounting piece. The base has extensions that fit within the fingers, and the fingers are gathered to reduce their length. This facilitates placement of a lead wire cable within each finger. Once the cables are placed within the fingers of the glove-like component, the base can be discarded and the terminal heads of the lead wire cables are grasped and pulled to extend the fingers of the glove-like component and to protect a length of the lead wire cables. If the base is a mounting piece, it is preferably retained for later uses and is made of a material such as rubber or plastic that can be sanitized and reused. The lead wire cable heads can be snapped directly onto sensor pads and will function through the material of the glove-like component, which is preferably a plastic. After use, the glove-like component is discarded and the lead wire cables and heads remain uncontaminated.