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ACELLULAR CORNEAS, METHODS OF PRODUCING THE SAME AND USES THEREOF
专利权人:
Shing-Jye CHEN;Fan-Wei TSENG;Dar-Jen HSIEH;Kai-Chi KU
发明人:
Shing-Jye CHEN,Fan-Wei TSENG,Kai-Chi KU,Dar-Jen HSIEH
申请号:
US15738644
公开号:
US20180296730A1
申请日:
2016.12.13
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A method of producing an acellular cornea includes steps of subjecting a cornea of an animal to a decellularization process, and has not the step of treating the cornea with a protease, a chelating agent, a detergent, a glycerol, or a combination thereof. When a native cornea is processed by the method, the native structure and conformation of the native cornea are preserved while immunogenic matters are reduced to a level that the thus produced cornea may serve as a three-dimensional scaffold for host cells to grow thereon after transplantation.
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