PRICE, JOHN D.,PICCARIELLO, THOMAS,OBERLENDER, ROBERT A.,MULHARE, MICHAELA E.,PALMER, SCOTT B.
申请号：
CA2816895
公开号：
CA2816895C
申请日:
2011.11.08
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Bismuth-containing compounds include bismuth and a biologically active agent coordinated to the bismuth. The biologically active agent includes at least one heteroatom configured for coordination with the bismuth. Coordination polymers include a polymer matrix that contains a bismuth- containing compound. Methods for modulating a pharmacokinetic property of a biologically active agent include coordinating the biologically active agent to bismuth to form a bismuth-containing compound, and administering the bismuth-containing compound orally to a patient. Methods for treating Parkinson's disease, methods for treating hypothyroidism, methods for treating ulcerative colitis, and methods for treating cancer each include administering a bismuth-containing compound to a patient.
