LEUNG, DONMIENNE DOEN MUN,LUAN, PENG,TANG, YING,WITCHER, DERRICK RYAN,YACHI, PIA PAULIINA
申请号：
CA2733497
公开号：
CA2733497C
申请日:
2009.07.29
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Monoclonalantibodies are provided that bind to theN--terminus of human hepcidin-25 andare characterized as having highaffinity and selectivity for thepolypeptide. The antibodies of theinvention are useful for increasingserum iron levels, reticulocyte count,red blood cell count, hemoglobin,and/or hematocrit in a human and forthe treatment of various disorders,such as anemia, in a human subject.The antibodies of the invention arealso useful as analytical tools, suchas in sandwich ELISA.
