SESSA, WILLIAM C.,DALBY, CHRISTINA M.,GALLANT-BEHM, CORRIE LYNN
申请号:
CA2997786
公开号:
CA2997786A1
申请日:
2016.09.22
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention provides miR-19 modulators and uses thereof, such as for promoting angiogenesis and/or wound healing with miR-19 inhibitors alone or in combination with other agents. The present invention also provides methods of treating or preventing arterial and cardiac conditions with a miR-19 inhibitor. Also provided are oligonucleotides with chemical motifs that are miR-19 inhibitors, and methods of using the oligonucleotides for inhibiting the function or activity of miR-19 in a subject in need thereof.