William C. SESSA,Christina Marie DALBY,Corrie Lynn GALLANT-BEHM
申请号:
US15762508
公开号:
US20180250325A1
申请日:
2016.09.22
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides miR-19 modulators and uses thereof, such as for promoting angiogenesis and/or wound healing with miR-19 inhibitors alone or in combination with other agents. The present invention also provides methods of treating or preventing arterial and cardiac conditions with a miR-19 inhibitor. Also provided are oligonucleotides with chemical motifs that are miR-19 inhibitors, and methods of using the oligonucleotides for inhibiting the function or activity of miR-19 in a subject in need thereof.