PROBLEM TO BE SOLVED: To provide a toothpaste composition for effectively preventing pain due to dentine hypersensitivity, immediately and sufficiently sealing openings in dentinal tubules in the surface of exposed dentine, and having excellent sustainability of the effect of inhibiting pain caused by dentine hypersensitivity.SOLUTION: The toothpaste composition includes the following components (A), (B) and (C). They are: (A) a low water-soluble powder selected from a fatty acid divalent metal salt (A-1) derived from a 12-18C saturated fatty acid, a fatty acid acyllysine (A-2) having an acyl group derived from a 12-18C saturated fatty acid, and a fatty acid acyltaurine divalent metal salt (A-3) having an acyl group derived from a 12-18C saturated fatty acid (B) a desensitizing agent selected from potassium nitrate, potassium citrate, strontium chloride and strontium acetate and (C) water.COPYRIGHT: (C)2013,JPO&INPIT【課題】象牙質知覚過敏症に起因する痛みを効果的に防止し、しかも、露出した象牙質の表面における象牙質細管の開口部を即効的かつ充分に封鎖し、象牙質知覚過敏症に起因する痛みの抑制効果の持続性に優れる歯磨組成物を提供する。【解決手段】次の成分(A)、(B)並びに(C):(A)炭素数12~18の飽和脂肪酸を由来とする脂肪酸二価金属塩(A-1)、炭素数12~18の飽和脂肪酸を由来とするアシル基を有する脂肪酸アシルリシン(A-2)、及び炭素数12~18の飽和脂肪酸を由来とするアシル基を有する脂肪酸アシルタウリン二価金属塩(A-3)から選ばれる水難溶性粉体、(B)硝酸カリウム、クエン酸カリウム、塩化ストロンチウム、及び酢酸ストロンチウムから選ばれる脱感作剤、並びに(C)水を含有する歯磨組成物。【選択図】図1