ВАЙБРЕХТ Мартин (NL),ГЕОРГИ Йенс Кристоф (NL),РИББИНГ Каролина М. (NL)
申请号：
RU2011143355/14
公开号：
RU2011143355A
申请日:
2010.02.18
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A method of creating an individual therapy plan, including (a) creating an initial therapy plan； (b) conducting therapy according to an initial therapy plan； wherein the initial therapy plan is based on the value of at least one biomarker from the patient. The method according to claim 1, further comprising (c) creating a corrected treatment plan taking into account the updated value of the measured biomarker； (d) conducting therapy according to the corrected treatment plan； at least one of the initial treatment plan and the corrected treatment plan is based on the value or updated value of at least one biomarker from the patient. 3. The method according to claim 1 or 2, in which individual biomarkers are associated with at least one of the sensitivities of healthy tissue and cancer tissue to therapy, and the method further includes establishing a value in accordance with individual biomarkers. The method according to claim 1 or 2, in which individual biomarkers are selected from the values of samples obtained in vitro, mass spectrometric protein signatures, medical history and medical history. The method of claim 4, wherein the in vitro samples are performed to determine the values of the in vitro samples that are cellular, proteomic or genetic in origin, wherein the in vitro samples contain cell counts, Hb, CRP, PSA, TNF-α, ferritin assays , transferrin, LDH, IL-6, hepsidin, creatinine, glucose, HbA1c, DNA terminal binding sites (DNA-EBC), HIF-1α, galectin-1, CAP43 and NDRG1 and / or telomere length. 6. The method according to claim 4, in which the biomarkers of anamnestic data and medical history contain the type of tumor, the degree of the tumor, the stage of the tumor, the location of the primary tumor, the degree of malignancy1. Способ создания индивидуального плана терапии, включающий(a) создание исходного плана терапии；(b) проведение терапии по исходному плану терапии；при этом исходный план терапии основан на значении по меньшей мере одного биомаркера от
