CHRISTIAN HUBSCHWERLEN,CORNELIA ZUMBRUNN ACKLIN,GEORG RUEEDI,JEAN-PHILIPPE SURIVET
申请号：
BR112014011064
公开号：
BR112014011064A2
申请日:
2012.11.07
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
Summary of Antibiotic Derivatives 2-oxo-oxazolidin-3,5-diyl The invention relates to the antibacterial compounds of formula II wherein r1a represents h or carboxy and r1b represents h, or r1a and r1b together represent either the group * -c (o) -nh-s- # or the group * -c (oh) = ns- # where “*” represents the binding point of r1a and “#” represents the binding point of r1b； R 2 represents h, (C 1 -C 3) alkyl, hydroxy (C 1 -C 3) alkyl, benzyl or (C 3 -C 5) cycloalkyl； R3 represents h or halogen； u represents n or cr 4； wherein r4 is h or (C1 -C3) alkoxy； a represents ch, b represents nh and m represents 1 or 2 and n represents 1 or 2； or a represents n, b is absent, m represents 2 and n represents 2； y represents ch or n； and q represents o or s； and salts of such compounds.resumo derivados de antibióticos 2-oxo-oxazolidin-3,5-diila a invenção refere-se aos compostos anti- bacterianos da fórmula i i em que r1a representa h ou carboxi e r1b representa h, ou r1a e r1b representam em conjunto seja o grupo *-c(o)-nh-s-# ou o grupo *-c(oh)=n-s-# em que “*” representa o ponto de ligação de r1a e “#” representa o ponto de ligação de r1b； r2 representa h, alquila(c1-c3), hidroxi-alquila(c1-c3), benzila ou cicloalquila(c3-c5)； r3 representa h ou halogênio； u representa n ou cr4； em que r4 é h ou alcoxi(c1-c3)； a representa ch, b representa nh e m representa 1 ou 2 e n representa 1 ou 2； ou a representa n, b está ausente, m representa 2 e n representa 2； y representa ch ou n； e q representa o ou s； e os sais de tais compostos.
