Provided is a holder for a surgical knife blade enabling only the surgical knife blade stored in a case to be attached to the holder without coming into contact with the surgical knife blade, providing easy and safe attachment to the holder, and further enabling bacteria and the like to be prevented from adhering.The holder for the surgical knife blade has a holder body that has a blade storage barrel and that is formed in an appropriate shape to grasp, a slide member that is supported slidably by the blade storage barrel, an attaching finger that is formed in part of the slide member to attach the surgical knife blade, a slide operating piece that is integrally formed with the slide member, a lock hook member that prevents the slide member from sliding, locking concave grooves that are disposed in a slide guide edge of the holder body which guides the slide member slidably and that engage in the lock hook member, and lever means, coupled to the slide member, for supporting the lock hook member while biasing the lock hook member toward the locking concave groove side, where the locking concave grooves are formed in an attachment position where the surgical knife blade is attached to the attaching finger in the slide member, in a use position where the attached blade is fixed, and in a storage position where the surgical knife blade is stored in the storage barrel.