GHOSH, SHYAMALI,KINNEY, WILLIAM A.,LAWSON, EDWARD C.,LUCI, DIANE K.,MARYANOFF, BRUCE E.,SOMMEN, FRANCOIS MARIA,PAN, YONGCHUN
申请号:
HK10102146.7
公开号:
HK1137353B
申请日:
2010.03.01
申请国别(地区):
HK
年份:
2014
代理人:
摘要:
The invention is directed to benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one Urotensin II receptor antagonists useful in treating or ameliorating a Urotensin-II mediated disorder. More specifically, the present invention relates to certain novel benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one compounds and methods for preparing compounds, compositions, intermediates and derivatives thereof. Pharmaceutical compositions and methods for treating or ameliorating a Urotensin-II mediated disorder using compounds of the invention are also described.