Ghosh Shyamali,William A Kinney,Edward C Lawson,Diane K Luci,Bruce E Maryanoff,Francois Maria Sommen
申请号：
US11881268
公开号：
US08759342B2
申请日:
2007.07.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention is directed to benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one Urotensin II receptor antagonists useful in treating or ameliorating a Urotensin-II mediated disorder. More specifically, the present invention relates to certain novel benzo[1,4]oxazin-3-one, benzo[1,4]thiazin-3-one and quinolin-2-one compounds and methods for preparing compounds, compositions, intermediates and derivatives thereof. Pharmaceutical compositions and methods for treating or ameliorating a Urotensin-II mediated disorder using compounds of the invention are also described.
