您的位置: 首页 > 农业专利 > 详情页

מטרים תרופה של חומצת אמינו המכילה פלואור
专利权人:
TAKASHI HASHIHAYATA;TAISHO PHARMACEUTICAL CO. LTD.;NORIKAZU OTAKE;KAZUNARI SAKAGAMI;NAOKI MIYAKOSHI
发明人:
TAKASHI HASHIHAYATA,NORIKAZU OTAKE,NAOKI MIYAKOSHI,KAZUNARI SAKAGAMI
申请号:
IL23589714
公开号:
IL235897A
申请日:
2014.11.25
申请国别(地区):
IL
年份:
2019
代理人:
摘要:
Provided are a fluorine-containing amino acid prodrug represented by general formula (I) that makes a fluorine-containing amino acid which is a group 2 metabotropic glutamate receptor agonist into a prodrug, or a pharmaceutically acceptable salt thereof. More specifically, provided is a prodrug that increases the in vivo exposure and enhances the oral absorbability and other mucosal absorbability of a parent compound that acts on group 2 metabotropic glutamate receptors as an agent for the treatment or prevention of diseases in which group 2 metabotropic glutamate receptors are said to be involved, such as: schizophrenia, anxiety disorder and its related diseases, depression, bipolar disorder, epilepsy, developmental disorders, sleep disorders, and other neuropsychiatric diseases; and drug dependence, cognitive disorders, Alzheimer's disease, Huntington's chorea, Parkinson's disease, movement disorders associated with muscular rigidity, cerebral ischemia, cerebral insufficiency, spinal cord disorders, cephalopathy, and other neurological diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充