MOSER, RUDOLF,GROEHN, VIOLA,BLATTER, FRITZ,SZELAGIEWICZ, MARTIN,BOEHNI STAMM, RUTH,RUETTIMANN, MARKUS,LAPADULA, GIUSEPPE
申请号：
CA3058289
公开号：
CA3058289A1
申请日:
2018.03.28
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention is directed to crystalline salt of 5-methyl-(6S)-tetrahydrofolic acid comprising (i) 5-methyl-(6S)-tetrahydrofolic acid, (ii) sodium and (iii) an organic base having a pKa value from 6 to 11； wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to the sodium is from :0.5 to 1:1.5 and the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to the organic base is 1:0.5 to 1:1.5 and/or hydrates and/or solvates thereof, as well as, a processes of obtaining the same.
