Rudolf MOSER,Viola GROEHN,Fritz BLATTER,Martin SZELAGIEWICZ,Ruth BOEHNI STAMM,Markus RUETTIMANN,Giuseppe LAPADULA
申请号:
US16499671
公开号:
US20200039982A1
申请日:
2018.03.28
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention is directed to crystalline salt of 5-methyl-(6S)-tetrahydrofolic acid comprising(i) 5-methyl-(6S)-tetrahydrofolic acid,(ii) sodium and(iii) an organic base having a pKa value from 6 to 11;wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to the sodium is from 1:0.5 to 1:1.5 and the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to the organic base is 1:0.5 to 1:1.5 and/or hydrates and/or solvates thereof, as well as, a processes of obtaining the same.