David M. Burns;Brian Metcalf;Colin Zhang;Ding-Quan Qian;Jincong Zhuo;Meizhong Xu;Chunhong He;Wenqing Yao
发明人:
Wenqing Yao,Chunhong He,David M. Burns,Jincong Zhuo,Meizhong Xu,Colin Zhang,Ding-Quan Qian,Brian Metcalf
申请号:
US13355219
公开号:
US08563570B2
申请日:
2012.01.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.