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COMBINATION DRUG THERAPIES FOR CANCER AND METHODS OF MAKING AND USING THEM
专利权人:
发明人:
申请号:
EP15814187.9
公开号:
EP3164121A4
申请日:
2015.07.01
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
In alternative embodiments, provided are therapeutic combinations, pharmaceutical compositions, formulations, kits and devices for treating, preventing or ameliorating a tumor or a cancer, and methods for treating, preventing or ameliorating a tumor or a cancer. In alternative embodiments, provided are therapeutic combinations, pharmaceutical compositions, formulations, kits and devices comprising: a beta adrenergic receptor antagonist (a “beta blocker”) a non-steroidal anti-inflammatory drug (a NSAID) and a therapeutic agent, compound or composition comprising: a H2-receptor antagonist (H2RA), a melatonin (or an N-acetyl-5-methoxy-tryptamine), a metformin, a quinoline (e.g., chloroquine), an immune checkpoint blockade agent, or an agent that blocks the interaction between a transmembrane programmed cell death 1 protein, or any combination thereof. In alternative embodiments, the therapeutic combinations of therapeutic agents or drugs further comprise an anti-cancer or anti-tumor antibody, a cytokine, and/or a chemotherapeutic agent.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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