H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.;TORREY PINES INSTITUTE FOR MOLECULAR STUDIES
发明人:
Said M. Sebti,Yangmei Li,Richard A. Houghten
申请号:
US15568931
公开号:
US10421764B2
申请日:
2016.04.25
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Compositions and methods for inhibits the binding of GTP to oncogenic mutant KRas are disclosed. These compositions may be used in method to treat a subject with cancer. In particular, the compositions may be used to treat cancers involving overactive Ras signaling.